
Ganoderic acid DM
CAS No. 173075-45-1
Ganoderic acid DM ( —— )
产品货号. M30882 CAS No. 173075-45-1
Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1).
纯度: >98% (HPLC)






规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥4040 | 有现货 |
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50MG | 获取报价 | 有现货 |
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100MG | 获取报价 | 有现货 |
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生物学信息
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产品名称Ganoderic acid DM
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1).
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产品描述Ganoderic acid DM is an antiandrogenic osteoclastogenesis inhibitor, it especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1), this suppression leads to the inhibition of dendritic cell-specific transmembrane protein (DC-STAMP) expression and reduces osteoclast fusion.
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体外实验Ganoderic acid DM (GADM) effectively inhibits cell proliferation and colony formation in MCF-7 human breast cancer cells, which was much stronger than that of MDA-MB-231 breast cancer cells.Ganoderic acid DM especially suppresses the expression of c-Fos and nuclear factor of activated T cells c1 (NFATc1). Ganoderic acid DM markedly suppressed the expression of cathepsin K and TRAP mRNA.Ganoderic acid DM induces autophagic apoptosis in non-small cell lung cancer cells by inhibiting the PI3K/Akt/mTOR activity.Cell Viability Assay Cell Line:MCF-7 and MDA-MB-231 cells.Concentration:0-100 μM.Incubation Time:48 h.Result:Decreased the cell viability in breast cancer cells.Cell Viability Assay Cell Line:RAW-D cells.Concentration:0-100 μg/mL.Incubation Time:0-100 μg/mL.Result:Clearly suppressed osteoclastogenesis from the RAW 264 cell D-clone.
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体内实验——
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同义词——
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通路Others
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靶点Other Targets
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受体——
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研究领域——
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适应症——
化学信息
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CAS Number173075-45-1
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分子量468.7
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分子式C30H44O4
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纯度>98% (HPLC)
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溶解度In Vitro:?DMSO : 50 mg/mL (106.68 mM)
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SMILES——
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册




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